- Clinicians may often be able to initiate all types of contraception safely during a patient’s initial office visit, even outside the first week of menses.
- The CDC issues guidelines to assist with choosing a suitable contraceptive method in the setting of coexisting medical problems.
- Long-acting reversible contraception such as intrauterine devices and the subdermal contraceptive implant are highly effective and require little action on the user’s part. Clinicians should offer them as first-line options whenever possible.
Latest Updates
- Pulmonary hypertension can be treated with single or combination therapy employing calcium channel blockers, phosphodiesterase inhibitors, guanylate cyclase stimulators, endothelin receptor antagonists, and prostanoids.
- Levosimendan is a calcium sensitizer used to treat cardiogenic shock and right heart failure.
- Clevidipine is an ultra-rapid acting calcium channel blocker used for perioperative hypertension management in cardiovascular and vascular diseases, neurosurgery, and surgery for pheochromocytoma.
Management of Drug Interactions between Anti-infectives and Common Anesthetics
- Rocuronium-induced neuromuscular blockade is potentiated by a synergistic effect of gentamicin and clindamycin, which may delay recovery.
- Penicillins form a complex with sugammadex, which may interfere with the therapeutically intended sugammadex-rocuronium complex.
- Ondansetron can decrease the analgesic efficacy of acetaminophen at high doses.
- Anesthesiologists are positioned to manage interactions between anesthetic agents and antimicrobials in the operating room.
- Improved intensive care management of patients with acute liver failure (ALF) has decreased the incidence of cerebral edema/intracranial hypertension
- High-volume plasma exchange improves overall survival in patients with ALF
- Improved understanding of the abnormalities of global hemostasis in patients with ALF
- Improved sanitation and mass vaccination has decreased the incidence of ALF due to hepatotrophic viruses
Acute Liver Failure
- Improved intensive care management of patients with acute liver failure (ALF) has decreased the incidence of cerebral edema/intracranial hypertension
- High-volume plasma exchange improves overall survival in patients with ALF
- Improved understanding of the abnormalities of global hemostasis in patients with ALF
- Improved sanitation and mass vaccination has decreased the incidence of ALF due to hepatotrophic viruses
- Improved intensive care management of patients with acute liver failure (ALF) has decreased the incidence of cerebral edema/intracranial hypertension
- High-volume plasma exchange improves overall survival in patients with ALF
- Improved understanding of the abnormalities of global hemostasis in patients with ALF
- Improved sanitation and mass vaccination has decreased the incidence of ALF due to hepatotrophic viruses
Injuries to the Upper Urogenital Tract
- Most grade III and IV injuries, including those with devitalized parenchymal fragments and urinary extravasation, are managed nonoperatively
- Angioembolization of persistent or delayed kidney bleeding (pseudoaneurysm) obviates the need for exploration in a majority of cases
- A high index of suspicion is necessary to diagnose a ureteral injury to prevent late complications such as urinoma, sepsis, and nephrectomy
Management of Chronic Kidney Disease and its Complications
- 2024 KDIGO Practice Guidelines
- Diabetes Canada 2018 Clinical Practice Guidelines for the Prevention and Management of Diabetes in Canada
- Diagnosis, Evaluation, Prevention, and Treatment of Chronic Kidney Disease-Mineral and Bone Disorder: Synopsis of the Kidney Disease: Improving Global Outcomes 2017 Clinical Practice Guideline Update.
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