- Updating consensus guideline recommendations up to January 2016
- Adding a duplex scan image showing a deep vein thrombosis (DVT) in the diagnosis section
- Adding a computed tomographic (CT) scan showing a pulmonary embolism (PE)
- Showing the various types of approved inferior vena cava filters
- Adding five separate flow-chart figures depicting a stepwise management algorithm for the evaluation and treatment of DVT and PE
- Adding a section on catheter-associated upper extremity thrombosis
- Adding a section on extended prophylaxis, the use of non–vitamin K antagonists, updates on stockings
- Writing five new multiple-choice questions based on the review
Latest Updates




Iatrogenic Withdrawal Syndromes in Children: A Review of Sedative and Analgesic Weaning
- Many iatrogenic withdrawal syndromes have been identified, the most common of which is opioid or benzodiazepine withdrawal. Generally speaking, the approach to treating opioid and/or benzodiazepine withdrawal is to provide enough medication to saturate target receptors, followed by a period of gradual dose reduction to allow the body to return to a state of homeostasis.
- The Neonatal Abstinence Score (NAS) was designed to assess withdrawal symptoms in infants with multiple drug exposure during pregnancy. Because the NAS was validated in infants, it is not applicable in older children with iatrogenic withdrawal. In recent years, withdrawal assessment tools for pediatrics have been developed for iatrogenic withdrawal to provide an objective assessment of withdrawal.
- There have been no randomized clinical trials that have compared the efficacy of various weaning strategies. However, a recent multicenter clinical trial, named the RESTORE trial, examined the effects of a standardized sedation protocol in pediatric intensive care units.


Iatrogenic Withdrawal Syndromes in Children: A Review of Sedative and Analgesic Weaning
- Many iatrogenic withdrawal syndromes have been identified, the most common of which is opioid or benzodiazepine withdrawal. Generally speaking, the approach to treating opioid and/or benzodiazepine withdrawal is to provide enough medication to saturate target receptors, followed by a period of gradual dose reduction to allow the body to return to a state of homeostasis.
- The Neonatal Abstinence Score (NAS) was designed to assess withdrawal symptoms in infants with multiple drug exposure during pregnancy. Because the NAS was validated in infants, it is not applicable in older children with iatrogenic withdrawal. In recent years, withdrawal assessment tools for pediatrics have been developed for iatrogenic withdrawal to provide an objective assessment of withdrawal.
- There have been no randomized clinical trials that have compared the efficacy of various weaning strategies. However, a recent multicenter clinical trial, named the RESTORE trial, examined the effects of a standardized sedation protocol in pediatric intensive care units.


- Early recognition of shock is difficult but essential for preservation of cellular and organ function and survival. The earliest clinical signs are nonspecific, with the initial inflammatory response including tachycardia, fevers, or cool or clammy skin.
- The approach to shock ultimately requires understanding and correcting its etiology (eg, antibiotics and source control for sepsis, thrombectomy after massive pulmonary embolus, hemorrhage control after trauma, and so forth). However, until these are diagnosed and addressed directly, clinicians ultimately have three approaches in their armamentarium: volume expansion, vasopressors, and cardioactive agents.
- The PAC was introduced in 1970. Its use increased over the next 3 decades and eventually was considered the standard of care for most critically ill patients. However, the use of PACs declined rapidly after the results of the randomized, controlled trial published in the New England Journal of Medicine revealing no benefit in high-risk surgical patients.


- Updating consensus guideline recommendations up to January 2016
- Adding a duplex scan image showing a deep vein thrombosis (DVT) in the diagnosis section
- Adding a computed tomographic (CT) scan showing a pulmonary embolism (PE)
- Showing the various types of approved inferior vena cava filters
- Adding five separate flow-chart figures depicting a stepwise management algorithm for the evaluation and treatment of DVT and PE
- Adding a section on catheter-associated upper extremity thrombosis
- Adding a section on extended prophylaxis, the use of non–vitamin K antagonists, updates on stockings
- Writing five new multiple-choice questions based on the review


Iatrogenic Withdrawal Syndromes in Children: A Review of Sedative and Analgesic Weaning
- Many iatrogenic withdrawal syndromes have been identified, the most common of which is opioid or benzodiazepine withdrawal. Generally speaking, the approach to treating opioid and/or benzodiazepine withdrawal is to provide enough medication to saturate target receptors, followed by a period of gradual dose reduction to allow the body to return to a state of homeostasis.
- The Neonatal Abstinence Score (NAS) was designed to assess withdrawal symptoms in infants with multiple drug exposure during pregnancy. Because the NAS was validated in infants, it is not applicable in older children with iatrogenic withdrawal. In recent years, withdrawal assessment tools for pediatrics have been developed for iatrogenic withdrawal to provide an objective assessment of withdrawal.
- There have been no randomized clinical trials that have compared the efficacy of various weaning strategies. However, a recent multicenter clinical trial, named the RESTORE trial, examined the effects of a standardized sedation protocol in pediatric intensive care units.


Cardiac Arrhythmias, Acute Coronary Syndromes, and Heart Failure in the Surgical Patient
- To recognize and treat important cardiac arrhythmias in the surgical patient using the latest advances
- Most up to date guidelines in management of Acute Coronary Syndrome (ACS) in Surgical Patients
- Recent progress in management ofheart failure in postoperative and traumatic patients


Cardiac Arrhythmias, Acute Coronary Syndromes, and Heart Failure in the Surgical Patient
- To recognize and treat important cardiac arrhythmias in the surgical patient using the latest advances
- Most up to date guidelines in management of Acute Coronary Syndrome (ACS) in Surgical Patients
- Recent progress in management ofheart failure in postoperative and traumatic patients
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