- Compression should be considered in patients with leg ulcers and ankle brachial index greater than 0.8.
- Pyoderma gangrenosum lesions ≤2 cm2 may benefit from topical/intralesional corticosteroids
- Chronic hydroxyurea therapy may lead to leg ulcers. Lesions typically occur near the malleolar area.
- Proper diagnosis/therapy of the underlying condition are key when clinicians are face atypical wounds.
Latest Updates


Diagnostic and Therapeutic Principles In Allergy
- Development of biologic therapies (primarily anti-cytokine) for the treatment of allergic diseases including asthma.
- Use of sIgE component testing for diagnosis and treatment of food allergy
- Early peanut introduction to prevent peanut allergy
- Novel treatment options for food allergy

Medical Management of Transplant Patients
- Alternatives therapies calcineurin inhibitors to prevent kidney allograft fibrosis.
- Maintenance immunosuppression with belatacept preserves glomerular filtration and increases kidney allograft survival.
- Better understanding and management of post transplant diabetes mellitus.
- The crush and snip technique is a quick and relatively bloodless method for skin removal in blepharoplasty.
- Care should be taken not to overresect fat and leave a sunken appearance to the upper eyelid.
- A simple Q-stick swab is one of the most useful instruments for the procedure of blepharoplasty.

Postresuscitation Management And Outcomes
- Therapeutic hypothermia is recommended for comatose survivors of cardiac arrest. The most recent evidence suggests that avoiding pyrexia may be the most important factor.
- The AHA recommends against prehospital cooling with cold intravenous fluid.
- Percutaneous coronary intervention is an independent predictor of survival.
- Prognostication is not recommended until 72 hours after return to normothermia in patients undergoing therapeutic hypothermia.
- Debriefing has been shown to improve several metrics of subsequent resuscitations.

Evaluation Of Elevated Transaminases In Children
- The threshold for the upper limit of normal for ALT is lower in children than previously reported based on studies of healthy, nonobese children.
- NAFLD needs to be identified and addressed in childhood as obese adolescents have a higher rate of complications in adulthood.
- NAFLD is a common indication for liver transplantation in adults.

- Recent advances in treatment of chronic HCV to include interferon-free direct-acting antiviral agent regimens
- Latest treatment recommendations, including special populations
- Issues surrounding treatment-emergent resistance-associated variants

Minimally Invasive Approaches to Forehead Rejuvenation
- Evolution in fixation techniques
- Endoscopic dissection
- Temporal changes in the Aesthetic Brow


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