- TAVR has emerged as a less invasive modality for valve replacement with similar results, employed in certain scenarios.
- 2017 AHA/ACC practice guideline updates on AVR indications.
- 2017 ESC/EACTS practice guideline updates on indications for AVR and TAVR, differentiating scenarios where each modality is most applicable.
Latest Updates
- TAVR has emerged as a less invasive modality for valve replacement with similar results, employed in certain scenarios.
- 2017 AHA/ACC practice guideline updates on AVR indications.
- 2017 ESC/EACTS practice guideline updates on indications for AVR and TAVR, differentiating scenarios where each modality is most applicable.
Metabolic Response to Critical Illness - Part 2
- Use of growth hormone for manipulation of metabolic response and muscle characteristics. This in combination with early physical therapy/exercise aids in preservation.
- Anti-cytokine antibodies for partial attenuation of metabolic response. These approaches have elucidated the complexity of mechanisms leading to the metabolic response of critically ill patients.
- Relatively recent adoption of the important role of the gut in metabolic response. This includes production of mediators and functioning as a barrier to bacteria which dramatically affect severity of metabolic response.
- Dyslipidemias are clinically important, principally because of their contribution to atherogenesis.
- Pancreatitis and fatty liver disease are less common but clinically significant manifestations of lipid disorders.
- Most recent practice guidelines for dyslipidemia diagnosis and management include the 2019 AAFP summary of the 2018 AHA/ACC practice guidelines, as well as the 2020 Veterans Health Administration guidelines.
- Dyslipidemias are clinically important, principally because of their contribution to atherogenesis.
- Pancreatitis and fatty liver disease are less common but clinically significant manifestations of lipid disorders.
- Most recent practice guidelines for dyslipidemia diagnosis and management include the 2019 AAFP summary of the 2018 AHA/ACC practice guidelines, as well as the 2020 Veterans Health Administration guidelines.
Metabolic Response to Critical Illness - Part 1
- Understanding the important role the gut has during injury and critical illness, for amino acid intake and altered circulation.
- Antibiotic-integrated catheters which delay complications of infection in suboptimal conditions.
Neurobiology of Psychotic Disorders
- Polygeneic risk stratification scores in development, with associated multi-biomarker assays in assessment of psychosis risk.
- Microbiome and potential link to psychosis and its interventions. It has been shown that gut microbiota may have an influential role on the course of psychosis and risk.
- Mindfulness therapies and their potential indication in psychosis treatment. Cognitive therapies show promising benefits in management of psychotic symptoms and course, and are outlined as an important aspect in therapy as per the 2020 APA practice guidelines.
Neurobiology of Psychotic Disorders
- Polygeneic risk stratification scores in development, with associated multi-biomarker assays in assessment of psychosis risk.
- Microbiome and potential link to psychosis and its interventions. It has been shown that gut microbiota may have an influential role on the course of psychosis and risk.
- Mindfulness therapies and their potential indication in psychosis treatment. Cognitive therapies show promising benefits in management of psychotic symptoms and course, and are outlined as an important aspect in therapy as per the 2020 APA practice guidelines.
