Latest Updates

Abnormal Menstrual Bleeding

Leanne Dumeny, MS, BS, MD-PhD, Candice P. Holliday, MD, JD, Chu Hsiao, BS, MD-PhD, Lisa Spiryda, MD-PhD
    • PALM-COEIN classification
    • Expansion of medical management strategies: IUD, tranexamic acid
    • Minimally invasive surgical options
    • Greater recognition of the psychosocial impact on quality of life

Diagnosis of Dyslipidemia

John D. Brunzell, MD, FACP, R Alan Failor, MD
    • Dyslipidemias are clinically important, principally because of their contribution to atherogenesis.
    • Pancreatitis and fatty liver disease are less common but clinically significant manifestations of lipid disorders.
    • Most recent practice guidelines for dyslipidemia diagnosis and management include the 2019 AAFP summary of the 2018 AHA/ACC practice guidelines, as well as the 2020 Veterans Health Administration guidelines.

Asthma

Anne E. Dixon, MA, BMBCH, Haitham Nsour, MBBS
    • ATS guidelines for exercise-induced bronchoconstriction, asthma in the elderly, and asthma in the workplace
    • ERS/ATS guideline for severe asthma discusses pharmacologic modalities of asthma management and bronchial thermoplasty.
    • 2020 GINA practice guidelines no longer recommend treatment with SABA alone, without inhaled ICS. Recommend that all adults and adolescents with asthma should receive ICS-containing controller treatment.
    • 2020 NAEPP practice guidelines delineating optimal treatment steps in adolescents and adults with asthma. This includes bronchial thermoplasty and immunotherapy.

Metabolic Response to Critical Illness - Part 1

Palmer Q. Bessey, MD
    • Understanding the important role the gut has during injury and critical illness, for amino acid intake and altered circulation.
    • Antibiotic-integrated catheters which delay complications of infection in suboptimal conditions.

Heart Failure

Mandeep R. Mehra, MD, Sachin P Shah, MD
    • Emerging evidence is refining an understanding of the role of the splanchnic circulation and the abdominal compartment in heart failure. The abdominal organs and splanchnic circulation appear to play an active role in volume distribution and renal filtration, thereby affecting balance between a compensated and a decompensated state. The understanding of the homeostatic role of the abdominal compartment in the compensated state and the maladaptive role in the decompensated state is evolving and may provide targets for new therapies and better application of available treatment strategies in the future.
    • 2017 focused update to ACC/AHA/HFSA practice guidelines for management of heart failure delineate further considerations for pharmacologic therapy and interventions.

Heart Failure

Mandeep R. Mehra, MD, Sachin P Shah, MD
    • Emerging evidence is refining an understanding of the role of the splanchnic circulation and the abdominal compartment in heart failure. The abdominal organs and splanchnic circulation appear to play an active role in volume distribution and renal filtration, thereby affecting balance between a compensated and a decompensated state. The understanding of the homeostatic role of the abdominal compartment in the compensated state and the maladaptive role in the decompensated state is evolving and may provide targets for new therapies and better application of available treatment strategies in the future.
    • 2017 focused update to ACC/AHA/HFSA practice guidelines for management of heart failure delineate further considerations for pharmacologic therapy and interventions.

Risk Factors and Epidemiology of Pulmonary Embolism

Aaron W Aday, MD, Aaron B Waxman, MD, PhD
    • Despite advances in diagnosis and treatment, pulmonary embolism accounts for nearly 1% of all cardiovascular-related deaths in the United States annually.
    • Pulmonary embolism is no longer considered an isolated event that requires short-term therapy but rather a chronic illness with long-term implications for patients.
    • 2020 ASH and 2019 ESC/ERS practice guidelines for pulmonary embolism delineate the most recent diagnostic and therapeutic approaches.

Risk Factors and Epidemiology of Pulmonary Embolism

Aaron W Aday, MD, Aaron B Waxman, MD, PhD
    • Despite advances in diagnosis and treatment, pulmonary embolism accounts for nearly 1% of all cardiovascular-related deaths in the United States annually.
    • Pulmonary embolism is no longer considered an isolated event that requires short-term therapy but rather a chronic illness with long-term implications for patients.
    • 2020 ASH and 2019 ESC/ERS practice guidelines for pulmonary embolism delineate the most recent diagnostic and therapeutic approaches.
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