Latest Updates

Adjuvant Radiation for Tissue Extremity and Truncal Sarcomas 

Melody Qu, MD, MPH, Nabil Wasif, MD, MPH
    • Indications for radiation therapy
    • Sequencing of radiation therapy
    • Technique for radiation delivery

Management of Locally Recurrent Sarcoma in the Extremity

Giorgos Karakousis, MD, Lauren Krumeich, MD, Madalyn G Neuwirth, MD
    • Management of local recurrence for extremity soft tissue sarcoma historically involved amputation, but practice has shifted to limb salvage therapy whenever feasible.
    • Proton therapy has developed as a means to deliver focused tumor-directed radiation therapy, particularly for patients with previous irradiation.
    • Limb perfusion or infusion has been used in the neoadjuvant or therapeutic setting to increase rates of limb salvage for locally advanced tumors.
    • Novel discoveries in genetic and molecular profiling are aimed at improving prognostication and therapy.
    • Intratumoral injections are being investigated for locally advanced tumors or in-transit disease. 

Malignant Tumors of the Spleen

Brandon Chapman, MD, Ana Gleisner, MD, PhD, Alessandro Paniccia, MD
    • Role of imaging for preoperative characterization of splenic lesions
    • Use of laparoscopy for splenectomy 

Signs of Abuse

David Juang, MD, FACS, FAAP, Richard Sola Jr, MD
    • History and physical findings in nonaccidental trauma
    • Diagnostic tools for nonaccidental trauma
    • Management of nonaccidental trauma injuries
    • Nonaccidental trauma checklists and algorithms 

Sarcoma: Vascular Tumors (EHE and Angiosarcoma)

Anne Grand'Maison, MD, John M Kane III, MD, Kilian Salerno, MD
    • The potential use of propranolol for beta-adrenergic blockade in the treatment of advanced angiosarcoma
    • Antiendoglin antibody (TRC 105) targeted therapy in clinical trials for the treatment of advanced angiosarcoma
    • The fusion gene WWTR1-CAMTA1 as an important diagnostic tool in challenging cases of epithelioid hemangioendothelioma

Sarcoma: Vascular Tumors (EHE and Angiosarcoma)

Anne Grand'Maison, MD, John M Kane III, MD, Kilian Salerno, MD
    • The potential use of propranolol for beta-adrenergic blockade in the treatment of advanced angiosarcoma
    • Antiendoglin antibody (TRC 105) targeted therapy in clinical trials for the treatment of advanced angiosarcoma
    • The fusion gene WWTR1-CAMTA1 as an important diagnostic tool in challenging cases of epithelioid hemangioendothelioma

Approach to Metastatic Melanoma

Alexandra Gangi, MD, Jonathan S Zager, MD, FACS
    • Intralesional therapy
    • Limb infusion
    • Percutaneous hepatic perfusion

Adjuvant and Neoadjuvant Therapy for Pancreatic Adenocarcinoma

Syed A Ahmed, MD, Gregory C Wilson, MD, Brent T Xia, MD
    • Review and analysis of previous adjuvant chemotherapy and adjuvant chemoradiation trials in resectable pancreatic cancer
    • Limitations outside of clinical trials with regard to omission and delayed initiation of adjuvant therapy
    • Highlighting of single- and multiinstitution findings with neoadjuvant therapy for resectable and locally advanced diseases
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