- Poor responders: mild ovarian stimulation resulted in similar clinical pregnancy rates as standard IVF protocols
- Single embryo transfer: newly established guidelines limit the number of embryos to transfer
- Frozen embryo transfer cycles: intramuscular progesterone for luteal support is superior to vaginal progesterone
Latest Updates
Epidemiology and Economics of Nephrolithiasis
- The prevalence and incidence of nephrolithiasis have increased over the last 30 years.
- Recurrence of nephrolithiasis is relatively common.
- Both environmental and dietary factors are associated with nephrolithiasis.
- Nephrolithiasis is associated with systemic disease like diabetes, hypertension, and obesity.
- Nephrolithiasis continues to be costly and burden on the health-care system
Regional Therapies for Extremity Sarcoma
- Identification of effective treatment strategies
- Improvements in patient risk stratification
- Neoadjuvant epirubicin and ifosfamide in a randomized clinical trial has shown to be effective in improving survival of patients affected by five high-risk soft tissue sarcoma histologies (undifferentiated pleomorphic sarcoma, myxoid liposarcoma, synovial sarcoma, malignant peripheral nerve sheath tumor, and leiomyosarcoma) of the trunk and extremities
- Inclusion of prognostic models in the eighth edition of the AJCC TNM staging system
Regional Therapies for Extremity Sarcoma
- Identification of effective treatment strategies
- Improvements in patient risk stratification
- Neoadjuvant epirubicin and ifosfamide in a randomized clinical trial has shown to be effective in improving survival of patients affected by five high-risk soft tissue sarcoma histologies (undifferentiated pleomorphic sarcoma, myxoid liposarcoma, synovial sarcoma, malignant peripheral nerve sheath tumor, and leiomyosarcoma) of the trunk and extremities
- Inclusion of prognostic models in the eighth edition of the AJCC TNM staging system
Adherence to Posttransplantation Medical Regimen
- Medication nonadherence is common post-liver transplantation.
- Nonadherence is associated with graft failure and posttransplantation hospitalizations.
- Risk factors for nonadherence include low social support, younger age, poor medication understanding, and depression.
- Validated measures to assess adherence include as self-report questionnaires, electronic monitoring devices, and immunosuppression levels.
- The monoclonal antibody trastuzumab has revolutionized the treatment of HER-2-positive breast cancer, resulting in improved patient outcomes.
- Dual anti-HER-2 therapy has been shown to result in increased pathologic complete response (pCR) rates in patients treated in the neoadjuvant setting.
- pCR has been shown to be associated with a good prognosis and outcome in patients receiving neoadjuvant chemotherapy.
- Novel anti-HER-2 agents are currently being investigated in ongoing trials.
Management of Acute Iliofemoral Deep Vein Thrombosis
- Mechanical removal of acute venous thrombus with increased safety
- Selection of catheter-directed thrombolysis in patients with thrombotic iliofemoral DVT
- Protocols of pharmacomechanical thrombolysis
- Using intravascular ultrasonography to guide intraoperative therapy
- The monoclonal antibody trastuzumab has revolutionized the treatment of HER-2-positive breast cancer, resulting in improved patient outcomes.
- Dual anti-HER-2 therapy has been shown to result in increased pathologic complete response (pCR) rates in patients treated in the neoadjuvant setting.
- pCR has been shown to be associated with a good prognosis and outcome in patients receiving neoadjuvant chemotherapy.
- Novel anti-HER-2 agents are currently being investigated in ongoing trials.
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