Latest Updates

Nerve Sheath Tumors: Malignant peripheral nerve sheath tumors, Schwannomas, and Neurofibromas

Alexander Lazar, MD, PhD, Ian E McCutcheon, Keila E Torres, MD, PhD, Wei-Lien Wang, MD
    • Oncogenic signatures responsible for the transformation MPNST include activation of the STAT3/HIF, catenin/Wnt and RHO/ROCK pathways.
    • MPNSTs often harbor recurrent inactivation of polycomb repressive complex 2 from somatic mutation of EED and/or SUZ12.
    • Genetic analysis revealed germline mutations in SMARCB1 in approximately 50% of individuals affected by familial schwannomatosis.
    • Germline mutations in LZTR1 were identified in about 80% of schwannomatosis cases lacking mutations in SMARCB1.

Biliary Tumors

Aslam Ejaz, MD, MPH, Bradley N Reames, MD, MS, Matthew J Weiss, MD

    Non-melanoma Skin

    Lindy L. Davis, MD, Emmanuel M. Gabriel, MD, PhD, Joseph J. Skitzki, MD

      Evaluation and Treatment of Pediatric Obesity

      Nirav K Desai, Samir Softic
        • 2017 Pediatric Obesity-Assessment, Treatment, and Prevention: An Endocrine Society Clinical Practive Guideline
        • 2017 NASPGHAN clinical practice guideline for the diagnosis and treatment of nonalcoholic fatty liver disease in children: recommendations from the Expert Committee on NAFLD (ECON) and the North American Society of Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN)

      Evaluation and Treatment of Pediatric Obesity

      Nirav K Desai, Samir Softic
        • 2017 Pediatric Obesity-Assessment, Treatment, and Prevention: An Endocrine Society Clinical Practive Guideline
        • 2017 NASPGHAN clinical practice guideline for the diagnosis and treatment of nonalcoholic fatty liver disease in children: recommendations from the Expert Committee on NAFLD (ECON) and the North American Society of Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN)

      Pancreatic and Adrenal Disorders and Considerations

      Jill Yaung, MD
        • Although diabetes mellitus is a frequent disease encountered in the intensive care unit, critically ill patients may have other reasons for glycemic dysfunction.
        • Hyperglycemia may cause multisystem dysfunction and poor outcomes, including increased in-hospital mortality. Hypoglycemia and glucose variability are both independent risk factors for increased mortality.
        • Adrenal insufficiency in critically ill patients without preexisting adrenal disease is known as critical illness-related corticosteroid insufficiency.

      Neuroendocrine Tumors

      Daniel A Anaya, MD, Jason B Fleming, MD, Benjamin D Powers, MD

        Principles and Techniques of Abdominal Access and Physiology of Pneumoperitoneum

        Jon C. Gould, MD, FACS, Kathleen Simon, MD
          • Decreasing pain at access incisions
          • Multi-modal pain management, TAPP block, opioid sparing analgesia.
          • Heated, humidified CO2.
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