- Recognition that TNBC is heterogeneous, improving understanding of TNBC biology, potentially enabling more precise therapies.
- Adding platinum salts and PARP inhibitors to neoadjuvant chemotherapy (NAC) significantly improves pathologic complete response.
- Axillary pathologic complete response (nodal downstaging) following NAC can result in more conservative axillary surgery.
- For residual disease post NAC, additional adjuvant therapy with capecitabine improves overall and disease-free survival.
Latest Updates
- 2017 ATC/IDSA/CDC Guidelines for the Diagnosis of Tuberculosis
- MDG goal to halt and reverse TB epidemic by 2015 has already been achieved
Imaging and Staging for Stomach Malignancy
- Endoscopic ultrasonography (EUS) is a currently the mainstay in diagnosis and staging of gastric tumors.
- EUS FNA offers precise diagnosis for primary tumors, local invasion, and lymph node sampling.
- PET can evaluate response to chemotherapy with early identification of non-responders and treatment modification.
Imaging and Staging for Stomach Malignancy
- Endoscopic ultrasonography (EUS) is a currently the mainstay in diagnosis and staging of gastric tumors.
- EUS FNA offers precise diagnosis for primary tumors, local invasion, and lymph node sampling.
- PET can evaluate response to chemotherapy with early identification of non-responders and treatment modification.
- Medical expulsion therapy may aid in the passage of distal ureteral stones and can be a useful adjunct in their management prior to more definitive surgical intervention.
- Medical expulsion therapy may increase the rate of ureteral stone passage and decrease time for expulsion.
- The data available at this time are strongest for the use of -antagonists in this role and may work best for distal ureteral stones from 5 to10 mm in size.
Electrical and Fire Safety in the OR
- Use of line isolation monitors to monitor the isolated power system ensuring that it is fully isolated from the ground
- Use of ground fault circuit interrupter to help prevent individuals from receiving an electrical shock in a grounded power system by monitoring both sides of the circuit for the equality of the current flow
- Discovery that sevoflurane and desiccated CO2 absorbent can undergo exothermic chemical reactions causing fires prompting preventive measures
The Respiratory System: Physiologic Assessment and Real-world Application
- Reflectance Pulse Oximetry: The use of backscattered light rather than transmitted light can be helpful in low-signal settings.
- Improved Signal Processing for Pulse Oximetry: Proprietary algorithms and advances in signal processing have improved the precision of pulse oximetry.
- Calorimetric Detection: Colorimetric CO2 detection can be used to ensure nasoenteric placement rather than respiratory placement.
The Respiratory System: Physiologic Assessment and Real-world Application
- Reflectance Pulse Oximetry: The use of backscattered light rather than transmitted light can be helpful in low-signal settings.
- Improved Signal Processing for Pulse Oximetry: Proprietary algorithms and advances in signal processing have improved the precision of pulse oximetry.
- Calorimetric Detection: Colorimetric CO2 detection can be used to ensure nasoenteric placement rather than respiratory placement.
